Description: On behalf of ICCVAM, NICEATM conducted a number of analyses to evaluate the use of the murine local lymph node assay (LLNA) to identify potential skin sensitizers. This list was compiled during those evaluations and includes chemicals with well-characterized activity as skin sensitizers or nonsensitizers. It was originally published in the 2009 ICCVAM Recommended Performance Standards for the Murine Local Lymph Node Assay. The list includes results (positive vs. negative) for each chemical as available for the LLNA, guinea pig maximization or Buehler test, human maximization test, and human patch test allergen tests.
Number of Chemicals: 22