Description: CHEMINV consists of the full list of unique DSSTox substance records mapped to the historical chemical inventory of physical samples registered by EPA's ToxCast Chemical Contractor (Evotec) in their sample tracking database since the launch of the ToxCast program in 2007. The CHEMINV file includes all chemical samples procured by Evotec for possible inclusion in EPA's ToxCast program since the start of the program in 2007, as well as a relatively small set of donated or EPA-supplied samples that were shipped to Evotec to be included in EPA's physical sample library. The list includes all samples received and registered by Evotec, but all samples were not necessarily solubilized or plated for testing, i.e., the full list includes volatiles, DMSO insolubles, depleted chemicals, and discarded chemicals deemed too dangerous for storage and handling. All physical samples plated for screening in the ToxCast program (TOXCAST), which includes EPA's full contribution to the Tox21 screening program (TOX21SL), are included as a subset of CHEMINV, as is the full list of samples currently available for ToxCast plating. Hence, the CHEMINV inventory file is a snapshot of all past and present samples. The CHEMINV file provides a complete historical record of chemicals that were prioritized for inclusion in EPA's ToxCast and Tox21 screening programs based on multiple criteria (toxicity data, exposure potential, use, etc.), and that were successfully procured by (or provided to) EPA's ToxCast Chemical Contractor (Evotec) for possible inclusion in those programs. The CHEMINV file is a subset of EPA's ChemTrack database (CHEMTRACK), the latter including all chemicals for which ToxCast or Tox21 screening data have been generated. CHEMTRACK additionally includes reference chemicals for which data were provided by ToxCast collaborators, as well as Tox21 chemicals not in EPA's physical inventory that were separately provided by Tox21 federal testing partners (the National Institutes of Health's National Toxicology Program and National Center for Advancing Translational Sciences). A detailed description of EPA's chemical management system and the DSSTox curation associated with chemical registration and mapping of the CHEMINV file is provided in the published document available for download at: https://www.epa.gov/chemical-research/toxcast-chemicals-data-management-and-quality-considerations-overview For more information on EPA’s ToxCast program, see: https://www.epa.gov/chemical-research/toxicity-forecasting https://www.epa.gov/chemical-research/toxicity-forecasting
Number of Chemicals: 5231